A course to optimize investment in the fight against HIV in Eastern Europe and Central Asia

Due to the fact that the Global Fund to Fight AIDS, Tuberculosis and Malaria is gradually reducing funding for epidemic programs in the region, the country are looking for ways to more effectively invest available domestic resources in this area, says UNAIDS on website.

"These changes are based on epidemiological and economic arguments. The economies of these countries is much better than the world average, so we expect that the region will increasingly deal with the existing burden of the disease on their own. The key task of the Global Fund, UNAIDS and other partners at this stage is to strengthen national measures and reduce the problem to a size that governments can handle on their own."- explains Dumitru Laticevschi, Regional Manager for the Eastern Europe and Central Asia Group of the Global Fund.

In a 2014 study of the effectiveness of HIV resource allocation in the EECA region, countries were encouraged to prioritize investment in the most cost-effective strategies, including updating HIV testing and treatment protocols, reducing treatment costs, and optimizing service delivery. The research is based on data from Mathematical Modeling Optima HIV, which has been used in more than 60 countries around the world to determine the most effective investment related to HIV.

A new wave of allocative research was recently completed in 11 countries in the region (Armenia, Azerbaijan, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Romania, Tajikistan, Ukraine and Uzbekistan). Individual reports with a set of recommendations for each country are available, as well as a regional report with aggregate analysis results for eleven countries.

"We provided technical support for the analytical work," - said Sherrie Kelly, head of the Burnett Institute's HIV, Tuberculosis and Malaria Program. - The data and the research results belong to the countries themselves. We only offer mathematical models. "

The modeling is based on demographic, epidemiological, behavioral and other data, as well as on cost estimates provided by national partners. The software component of costs and the algorithm of optimization of resources are superimposed on the model of epidemic. The results are intensively discussed and confirmed by national teams and key stakeholders from the respective countries. The UNAIDS Secretariat facilitates the whole process to further strengthen the capacity of national partners to optimize health care costs.

The new COVID-19 Law Lab will provide important information and support to combat COVID-19 worldwide

The COVID-19 Law Lab initiative was created to ensure the collection and sharing of legal documents from more than 190 countries. This will help to create and implement a strong legal framework to combat the pandemic, which will protect the health and well-being of individuals or communities, in line with international human rights standards.

Detailed laws will help build strong health care systems, test and register safe and effective drugs and vaccines, and enforce healthier and safer public spaces and workplaces. In addition, ill-conceived and ineffective regulations, which are not backed up by enforcement mechanisms, can harm marginalized populations, promote stigma and discrimination, and hamper pandemic remedies.

"Harmful legislation can increase stigma and discrimination, restrict people's rights and disrupt health measures," said Winnie Byanyima, UNAIDS Executive Director. "In order for pandemic measures to be effective, humane and sustainable, States must use the law as a tool to protect the rights and dignity of the people affected by COVID-19."

The COVID-19 Law Lab is a database of legislative action taken by countries in response to a pandemic. These include declarations of emergency, isolation and quarantine measures, disease surveillance and legal measures relating to the wearing of masks, social distancing, and access to medicines and vaccines.

COVID-19 Law Lab is a joint project of the United Nations Development Program, the World Health Organization, UNAIDS and the Institute of National and International Health Law. O'Neill at Georgetown University.

The story of one vaccine: how to find a cure for HIV HIV

About 40 million people living with HIV are registered in the world. In Ukraine, every hundredth citizen aged 15 to 49 is infected.

Scientists have been trying for years to create a drug that can affect a wide range of strains of human immunodeficiency virus, but success is difficult. The virus is constantly mutating, so a person can not develop immunity to it.

On September 2, 2000, a prototype of the AIDS vaccine was introduced for the first time, gazeta.ua reports. The results of the first large clinical trial of the HIV vaccine, AIDSVax, were published in 2003. The vaccine contained fragments of the virus - gp120 glycoproteins. Its ineffectiveness has been demonstrated in clinical trials.

Then they set out to develop a vaccine aimed at stimulating cellular rather than humoral immunity. However, a study called STEP stopped in 2007.

Another large-scale study was led by Harvard Medical School professor Dan Baruk. The researchers tested different vaccine options on healthy participants aged 18 to 50 who were not infected with HIV. Each of them was vaccinated for 48 weeks. All vaccines were effective and safe for patients. At the same time, the researchers vaccinated the macaque against an HIV-like virus, and the vaccine protected the vast majority of the subjects. However, Professor Dan Baruk says it is too early to draw conclusions about the vaccine's ability to prevent infection.

In fact, this is not the first human vaccine to be tested on humans. For example, one of them was tested in Thailand. It showed a reduction in infection by almost a third. But these indicators are not enough for its widespread use.

Currently, the modified RV144 vaccine is being tested in a phase III clinical trial. The results will be published in 2021.

 

Distance learning in the field of HIV: Papua New Guinea provides virtual training for doctors

Distance learning is a new milestone in the development of the education system. Changes in the field of medicine, in particular, the direction of the fight against HIV and prevention of the spread of human immunodeficiency virus have not escaped. For example, the National Department of Health of Papua New Guinea has launched the country's first virtual training program for doctors prescribing antiretroviral treatment.

It is reported that in the 30 days since the launch of the program, 105 participants have registered, 70% of whom have not had the opportunity to attend any other training events in the last three years.

Participants gained access to 21 video lectures with a total duration of more than six hours. The materials are based on Google Class technology and focus on topics such as HIV treatment, care and maintenance, and monitoring and evaluation tools. Training materials include video lectures and test tasks that must be completed within seven days of registration.

This method of training has significantly reduced the costs of both organizers and participants. All doctors need to be successful is, for example, access to the Internet, an active e-mail account for registration, minimal computer skills, and so on. For some time, teachers remain available to health professionals and through the platform are ready to provide advice and help to understand in more detail the issues that may arise after the course.

The organizers and staff of the program are representatives of the National Technical Working Group on HIV, which includes the UNAIDS regional office. The Google Class platform is free; all material is stored on Google Drive, which remains available through Google's regular account.

Later, after the virtual classes, the training will be consolidated by control visits and field training sessions.

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